Synthesis, Characterisation and Biological Activity of Thienoyl- and Furanoyl-Derived Schiff-Base Compounds With 3d Metal Ions

Cobalt(ll), copper(ll), nickel(ll) and zinc(ll) metal complexes of 2-carboxybenzylidene thienoylhydrazide HL(1) and 2-carboxybenzylidene furenoylhydrazide HL(2) of the type [M(L)(2).Cl(2)] have been prepared where M = Co(ll) and Ni(ll) and L = HL(1) and HL(2) (Fig 1) and characterized by their physical, analytical and spectral studies. The different mode of chelation of the ligands with metals and the effect of these metals on their biological properties is discussed.